New screenshots released today introduce the new starting point in Pokemon Black Version 2 and White Version 2. Aspertia City is a location new to the series, though of course "new" is relative in the world of Pokemon. From that location, you'll begin your investigation of how the Unova setting has changed since the events of two years ago. And you'll catch lots of Pokemon and fight gym leaders and stuff.
Nintendo also sent out the new box arts, allowing you to see Black Kyurem and White Kyurem facing each other down just as they will on retail shelves. Unless they're shelved in a different order, in which case they'll be defiantly facing away from each other.