A number of independent games retailers have joined forces with the Entertainment Retailers Association to call for action against R4 cards.
Shop owners have claimed the prevalence of the device has cost them much needed revenue and significantly damaged sales of DS software.
"Since the appearance of these cards we have noticed a downturn in the sale of our DS games," said indie shop owner Steve Pooler to MCV. "It is frustrating as we could make decent margins on the DS. Sadly this has now been eroded with the growth of these cards."
If one were so inclined, they could buy an R4 card for around £20 from respected online retailers, and then illegally download games for nothing. In comparison, DS games can cost £29.99 each.
Unsurprisingly, the ERA isn't happy about that. Representative Kim Bayley said: "We expected that the piracy suffered by movies and music would make its way to games, and it's something we all need to get a grip on.
"The industry needs to be on its toes and take advantage of the digital models already in place."