High Voltage Software experimented with support for the MotionPlus peripheral in The Conduit, but omitted it from the final game. Sega announced today that the sequel will allow players to augment the game's controls with the underused gyroscope peripheral.
According to the announcement, in addition to general response improvements, the MotionPlus will improve "edge tracking and transitions to pointer control" -- which sounds like it should make the experience of accidentally pointing off screen while turning somewhat less infuriating.
If you are living a MotionMinus life and still want to play Conduit 2, don't worry: it's totally optional. Conduit 2 will be out this fall.