In an interview Greg Johnson, co-creator of the cult-classic Sega Genesis game Toe Jam & Earl confirmed he was developing an exclusive DS game, saying:
"I can probably say it's a game for the Nintendo DS and it involves very emotionally expressive AI stuff. It's really targeted at non-gamers, and like ToeJam & Earl it's quirky and kind of off-the-wall. I have a little development studio - just eight of us - in Point Richmond called HumaNature Studios and I work with a great bunch. It's been worth the wait to do this."
411 Mania Games will bring you more news on this as-yet untitled game as it develops.